Function and Biology

Crystal structure of a complex of griffithsin with mannose at 1.78 A resolution.

Source organism: Griffithsia
Biochemical function: N-acetylgalactosamine binding
Biological process: not assigned
Cellular component: not assigned

GO terms

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned

Sequence family

Pfam Protein family (Pfam)
PF01419
Domain description: Jacalin-like lectin domain
Occurring in:
  1. Griffithsin
The deposited structure of PDB entry 2guc contains 2 copies of Pfam domain PF01419 (Jacalin-like lectin domain) in Griffithsin. Showing 1 copy in chain A.

InterPro InterPro annotations
IPR001229
Domain description: Jacalin-like lectin domain
Occurring in:
  1. Griffithsin
IPR036404
Domain description: Jacalin-like lectin domain superfamily
Occurring in:
  1. Griffithsin

Structure domain

CATH CATH domain
2.100.10.30
Class: Mainly Beta
Architecture: Aligned Prism
Topology: Vitelline Membrane Outer Layer Protein I, subunit A
Homology: Jacalin-like lectin domain
Occurring in:
  1. Griffithsin
The deposited structure of PDB entry 2guc contains 2 copies of CATH domain 2.100.10.30 (Vitelline Membrane Outer Layer Protein I, subunit A) in Griffithsin. Showing 1 copy in chain A.
SCOP SCOP annotation
51102
Class: All beta proteins
Fold: beta-Prism I
Superfamily: Mannose-binding lectins
Occurring in:
  1. Griffithsin
The deposited structure of PDB entry 2guc contains 2 copies of SCOP domain 51102 (Mannose-binding lectins) in Griffithsin. Showing 1 copy in chain A.