Function and Biology Details
Reaction catalysed:
ATP + [receptor-protein] = ADP + [receptor-protein] phosphate
Biochemical function:
Biological process:
Cellular component:
Sequence domains:
- Transforming growth factor-beta, C-terminal
- Ser/Thr protein kinase, TGFB receptor
- Snake toxin-like superfamily
- Cystine-knot cytokine
- Activin types I and II receptor domain
- Transforming growth factor beta, conserved site
- Bone morphogenetic protein 2, TGF-beta-like domain
- Transforming growth factor-beta-related
Structure analysis Details
Assembly composition:
hetero tetramer (preferred)
PDBe Complex ID:
PDB-CPX-146282 (preferred)
Entry contents:
3 distinct polypeptide molecules
Macromolecules (3 distinct):
Ligands and Environments
No bound ligands
No modified residues
Experiments and Validation Details
X-ray source:
RIGAKU
Spacegroup:
P212121
Expression system: Escherichia coli