2hfg

X-ray diffraction
2.61Å resolution

Crystal structure of hBR3 bound to CB3s-Fab

Released:
Model geometry
Fit model/data

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero trimer (preferred)
PDBe Complex ID:
PDB-CPX-212387 (preferred)
Entry contents:
3 distinct polypeptide molecules
Macromolecules (3 distinct):
CB3s Fab light chain (kappa) Chain: L
Molecule details ›
Chain: L
Length: 214 amino acids
Theoretical weight: 23.25 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
Structure domains: Immunoglobulins
Ig-like domain-containing protein Chain: H
Molecule details ›
Chain: H
Length: 232 amino acids
Theoretical weight: 24.41 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q6N093 (Residues: 5-70, 71-77, 78-194; Coverage: 46%)
Gene name: DKFZp686I04196
Sequence domains:
Structure domains: Immunoglobulins
Tumor necrosis factor receptor superfamily member 13C Chain: R

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

wwPDB Validation report is not available for this entry.
X-ray source: ALS BEAMLINE 5.0.1
Spacegroup: I213
Unit cell:
a: 146.408Å b: 146.408Å c: 146.408Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.201 0.195 0.252
Expression system: Escherichia coli