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- Temozolomide and Pituitary Tumors: Current Understanding, Unresolved Issues, and Future Directions. Syro LV, Rotondo F, Camargo M, Ortiz LD, Serna CA, Kovacs K. Front Endocrinol (Lausanne) 9 318 (2018)
- Regulation and Modulation of Human DNA Polymerase δ Activity and Function. Lee MYWT, Wang X, Zhang S, Zhang Z, Lee EYC. Genes (Basel) 8 E190 (2017)
- DNA alkylation lesion repair: outcomes and implications in cancer chemotherapy. Peng Y, Pei H. J Zhejiang Univ Sci B 22 47-62 (2021)
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- A Photosensitized Singlet Oxygen (1O2) Toolbox for Bio-Organic Applications: Tailoring 1O2 Generation for DNA and Protein Labelling, Targeting and Biosensing. Aerssens D, Cadoni E, Tack L, Madder A. Molecules 27 778 (2022)
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- Establishing Linkages Among DNA Damage, Mutagenesis, and Genetic Diseases. Basu AK, Essigmann JM. Chem Res Toxicol 35 1655-1675 (2022)
- The complexity and regulation of repair of alkylation damage to nucleic acids. Tsao N, Schärer OD, Mosammaparast N. Crit Rev Biochem Mol Biol 56 125-136 (2021)
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- Etheno adducts: from tRNA modifications to DNA adducts and back to miscoding ribonucleotides. Guengerich FP, Ghodke PP. Genes Environ 43 24 (2021)
- Bst polymerase - a humble relative of Taq polymerase. Oscorbin I, Filipenko M. Comput Struct Biotechnol J 21 4519-4535 (2023)
- The DNA Alkyltransferase Family of DNA Repair Proteins: Common Mechanisms, Diverse Functions. Tessmer I, Margison GP. Int J Mol Sci 25 463 (2023)
Articles citing this publication (62)
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- Visualizing transient Watson-Crick-like mispairs in DNA and RNA duplexes. Kimsey IJ, Petzold K, Sathyamoorthy B, Stein ZW, Al-Hashimi HM. Nature 519 315-320 (2015)
- The structure of a high fidelity DNA polymerase bound to a mismatched nucleotide reveals an "ajar" intermediate conformation in the nucleotide selection mechanism. Wu EY, Beese LS. J Biol Chem 286 19758-19767 (2011)
- Adaptive ligand binding by the purine riboswitch in the recognition of guanine and adenine analogs. Gilbert SD, Reyes FE, Edwards AL, Batey RT. Structure 17 857-868 (2009)
- Dynamic basis for dG•dT misincorporation via tautomerization and ionization. Kimsey IJ, Szymanski ES, Zahurancik WJ, Shakya A, Xue Y, Chu CC, Sathyamoorthy B, Suo Z, Al-Hashimi HM. Nature 554 195-201 (2018)
- DNA damage alters DNA polymerase delta to a form that exhibits increased discrimination against modified template bases and mismatched primers. Meng X, Zhou Y, Zhang S, Lee EY, Frick DN, Lee MY. Nucleic Acids Res 37 647-657 (2009)
- The mechanism of the translocation step in DNA replication by DNA polymerase I: a computer simulation analysis. Golosov AA, Warren JJ, Beese LS, Karplus M. Structure 18 83-93 (2010)
- Structural factors that determine selectivity of a high fidelity DNA polymerase for deoxy-, dideoxy-, and ribonucleotides. Wang W, Wu EY, Hellinga HW, Beese LS. J Biol Chem 287 28215-28226 (2012)
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- Direct NMR Evidence that Transient Tautomeric and Anionic States in dG·dT Form Watson-Crick-like Base Pairs. Szymanski ES, Kimsey IJ, Al-Hashimi HM. J Am Chem Soc 139 4326-4329 (2017)
- Transcription elongation past O6-methylguanine by human RNA polymerase II and bacteriophage T7 RNA polymerase. Dimitri A, Burns JA, Broyde S, Scicchitano DA. Nucleic Acids Res 36 6459-6471 (2008)
- Structural and Kinetic Studies of the Effect of Guanine N7 Alkylation and Metal Cofactors on DNA Replication. Kou Y, Koag MC, Lee S. Biochemistry 57 5105-5116 (2018)
- Metal-dependent conformational activation explains highly promutagenic replication across O6-methylguanine by human DNA polymerase β. Koag MC, Lee S. J Am Chem Soc 136 5709-5721 (2014)
- Roles of translesion synthesis DNA polymerases in the potent mutagenicity of tobacco-specific nitrosamine-derived O2-alkylthymidines in human cells. Weerasooriya S, Jasti VP, Bose A, Spratt TE, Basu AK. DNA Repair (Amst) 35 63-70 (2015)
- The Closing Mechanism of DNA Polymerase I at Atomic Resolution. Miller BR, Beese LS, Parish CA, Wu EY. Structure 23 1609-1620 (2015)
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- Lack of DNA mismatch repair protein MSH6 in the rat results in hereditary non-polyposis colorectal cancer-like tumorigenesis. van Boxtel R, Toonen PW, van Roekel HS, Verheul M, Smits BM, Korving J, de Bruin A, Cuppen E. Carcinogenesis 29 1290-1297 (2008)
- Molecular Mechanisms of Malignant Transformation by Low Dose Cadmium in Normal Human Bronchial Epithelial Cells. Cartularo L, Kluz T, Cohen L, Shen SS, Costa M. PLoS One 11 e0155002 (2016)
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- Mechanisms of Insertion of dCTP and dTTP Opposite the DNA Lesion O6-Methyl-2'-deoxyguanosine by Human DNA Polymerase η. Patra A, Zhang Q, Guengerich FP, Egli M. J Biol Chem 291 24304-24313 (2016)
- DNA Polymerases η and ζ Combine to Bypass O(2)-[4-(3-Pyridyl)-4-oxobutyl]thymine, a DNA Adduct Formed from Tobacco Carcinogens. Gowda AS, Spratt TE. Chem Res Toxicol 29 303-316 (2016)
- Noncognate DNA damage prevents the formation of the active conformation of the Y-family DNA polymerases DinB and DNA polymerase κ. Nevin P, Lu X, Zhang K, Engen JR, Beuning PJ. FEBS J 282 2646-2660 (2015)
- Prechemistry nucleotide selection checkpoints in the reaction pathway of DNA polymerase I and roles of glu710 and tyr766. Bermek O, Grindley ND, Joyce CM. Biochemistry 52 6258-6274 (2013)
- DNA replication studies of N-nitroso compound-induced O6-alkyl-2'-deoxyguanosine lesions in Escherichia coli. Wang P, Leng J, Wang Y. J Biol Chem 294 3899-3908 (2019)
- The use of an artificial nucleotide for polymerase-based recognition of carcinogenic O6-alkylguanine DNA adducts. Wyss LA, Nilforoushan A, Williams DM, Marx A, Sturla SJ. Nucleic Acids Res 44 6564-6573 (2016)
- Atomic Insight into the Altered O6-Methylguanine-DNA Methyltransferase Protein Architecture in Gastric Cancer. Chikan NA, Bukhari S, Shabir N, Amin A, Shafi S, Qadri RA, Patel TN. PLoS One 10 e0127741 (2015)
- Bypass of the Major Alkylative DNA Lesion by Human DNA Polymerase η. Koag MC, Jung H, Kou Y, Lee S. Molecules 24 E3928 (2019)
- Insights into the effect of minor groove interactions and metal cofactors on mutagenic replication by human DNA polymerase β. Koag MC, Lee S. Biochem J 475 571-585 (2018)
- Mutagenicity associated with O6-methylguanine-DNA damage and mechanism of nucleotide flipping by AGT during repair. Jena NR, Bansal M. Phys Biol 8 046007 (2011)
- Synthesis, Characterization, and Repair of a Flexible O(6) -2'-Deoxyguanosine-alkylene-O(6) -2'-deoxyguanosine Intrastrand Cross-Link. O'Flaherty DK, Wilds CJ. Chemistry 21 10522-10529 (2015)
- Effects of N(2)-alkylguanine, O(6)-alkylguanine, and abasic lesions on DNA binding and bypass synthesis by the euryarchaeal B-family DNA polymerase vent (exo(-)). Lim S, Song I, Guengerich FP, Choi JY. Chem Res Toxicol 25 1699-1707 (2012)
- Exploring the roles of nucleobase desolvation and shape complementarity during the misreplication of O(6)-methylguanine. Chavarria D, Ramos-Serrano A, Hirao I, Berdis AJ. J Mol Biol 412 325-339 (2011)
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- Measuring thermodynamic preferences to form non-native conformations in nucleic acids using ultraviolet melting. Rangadurai A, Shi H, Xu Y, Liu B, Abou Assi H, Boom JD, Zhou H, Kimsey IJ, Al-Hashimi HM. Proc Natl Acad Sci U S A 119 e2112496119 (2022)
- O(6)-Alkylguanine DNA Alkyltransferase Repair Activity Towards Intrastrand Cross-Linked DNA is Influenced by the Internucleotide Linkage. O'Flaherty DK, Wilds CJ. Chem Asian J 11 576-583 (2016)
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- DNA Polymerase ν Rapidly Bypasses O6-Methyl-dG but Not O6-[4-(3-Pyridyl)-4-oxobutyl-dG and O2-Alkyl-dTs. Gowda AS, Spratt TE. Chem Res Toxicol 29 1894-1900 (2016)
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- Kinetics of deoxy-CTP incorporation opposite a dG-C8-N-2-aminofluorene adduct by a high-fidelity DNA polymerase. Burnouf DY, Wagner JE. J Mol Biol 386 951-961 (2009)
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- Dynamic basis for dA•dGTP and dA•d8OGTP misincorporation via Hoogsteen base pairs. Gu S, Szymanski ES, Rangadurai AK, Shi H, Liu B, Manghrani A, Al-Hashimi HM. Nat Chem Biol 19 900-910 (2023)
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- Human O6 -methylguanine-DNA methyltransferase containing C145A does not prevent hepatocellular carcinoma in C3HeB/FeJ transgenic mice. Herzig MC, Hildreth K, Huamani J, Perez M, Goins BA, McMahan CA, Reddick RL, Walter CA. Mol Carcinog 52 275-285 (2013)
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