› 2i4k

Solution NMR

Solution Structure of the PX domain of Sorting Nexin 1

Released:
DOI: 10.2210/pdb2i4k/pdb
PDB entry 2i4k coloured by chain, ensemble of 10 models, front view.
PDB entry 2i4k coloured by chain, ensemble of 10 models, side view.
PDB entry 2i4k coloured by chain, ensemble of 10 models, top view.
Source organism: Homo sapiens
Primary publication:
Determinants of the endosomal localization of sorting nexin 1.
Zhong Q, Watson MJ, Lazar CS, Hounslow AM, Waltho JP, Gill GN
Mol Biol Cell 16 2049-57 (2005)
PMID: 15673616

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-171773 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Sorting nexin-1 Chain: A
Molecule details ›
Chain: A
Length: 128 amino acids
Theoretical weight: 14.7 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q13596 (Residues: 142-269; Coverage: 25%)
Gene name: SNX1
Sequence domains: PX domain
Structure domains: Phox-like domain

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Chemical shift assignment: 83%
Refinement method: molecular dynamics, simulated annealing, torsion angle dynamics
Expression system: Escherichia coli

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Citations

6 review citations

Membrane recognition by phospholipid-binding domains.
Lemmon MA. (2008)
5 more

9 mentions without citation

Translation of the phosphoinositide code by PI effectors.
Kutateladze TG. (2010)
8 more