› 2i4s

X-ray diffraction
1.92Å resolution

PDZ domain of EpsC from Vibrio cholerae, residues 204-305

Released:
DOI: 10.2210/pdb2i4s/pdb
PDB entry 2i4s coloured by chain, front view.
PDB entry 2i4s coloured by chain, side view.
PDB entry 2i4s coloured by chain, top view.
Source organism: Vibrio cholerae
Primary publication:
Structural and functional studies of EpsC, a crucial component of the type 2 secretion system from Vibrio cholerae.
Korotkov KV, Krumm B, Bagdasarian M, Hol WG
J Mol Biol 363 311-21 (2006)
PMID: 16978643

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-155344 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Type II secretion system protein C Chains: A, B
Molecule details ›
Chains: A, B
Length: 105 amino acids
Theoretical weight: 12.16 KDa
Source organism: Vibrio cholerae
Expression system: Escherichia coli
UniProt:
  • Canonical: P45777 (Residues: 204-305; Coverage: 33%)
Gene names: VC_2734, epsC
Structure domains: Pdz3 Domain

Ligands and Environments

No bound ligands
1 modified residue:
Ligand MSE 12 x MSE

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 19-BM, null
Spacegroup: C2
Unit cell:
a: 111.244Å b: 25.499Å c: 87.654Å
α: 90° β: 125.38° γ: 90°
R-values:
R R work R free
0.179 0.176 0.236
Expression system: Escherichia coli

Quick links

Citations

9 review citations

Secretins: dynamic channels for protein transport across membranes.
Korotkov et al. (2011)
8 more

4 mentions without citation

The type II secretion system: biogenesis, molecular architecture and mechanism.
Korotkov et al. (2012)
3 more