› 2if1

Solution NMR

HUMAN TRANSLATION INITIATION FACTOR EIF1, NMR, 29 STRUCTURES

Released:
DOI: 10.2210/pdb2if1/pdb
PDB entry 2if1 coloured by chain, ensemble of 29 models, front view.
PDB entry 2if1 coloured by chain, ensemble of 29 models, side view.
PDB entry 2if1 coloured by chain, ensemble of 29 models, top view.
Source organism: Homo sapiens
Primary publication:
Structure and interactions of the translation initiation factor eIF1.
Fletcher CM, Pestova TV, Hellen CU, Wagner G
EMBO J 18 2631-7 (1999)
PMID: 10228174

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-154404 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Eukaryotic translation initiation factor 1 Chain: A
Molecule details ›
Chain: A
Length: 126 amino acids
Theoretical weight: 14.33 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P41567 (Residues: 1-113; Coverage: 100%)
Gene names: EIF1, SUI1
Sequence domains: Translation initiation factor SUI1
Structure domains: SUI1-like domain

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: simulated annealing
Expression system: Escherichia coli BL21(DE3)

Quick links

Citations

20 review citations

The scanning mechanism of eukaryotic translation initiation.
Hinnebusch AG. (2014)
19 more

11 mentions without citation

Molecular view of 43 S complex formation and start site selection in eukaryotic translation initiation.
Lorsch et al. (2010)
10 more