› 2ifc

X-ray diffraction
1.7Å resolution

The Structure of the Binary Complex of Oxalateacetate with Citrate Synthase from the Thermophilic Archaeon Thermolasma acidophilum

Released:
DOI: 10.2210/pdb2ifc/pdb
PDB entry 2ifc coloured by chain, front view.
PDB entry 2ifc coloured by chain, side view.
PDB entry 2ifc coloured by chain, top view.
Source organism: Thermoplasma acidophilum
Entry author: Lehmann C

Function and Biology Details

Reaction catalysed: 
Acetyl-CoA + H(2)O + oxaloacetate = citrate + CoA
Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-539810 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Citrate synthase Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 385 amino acids
Theoretical weight: 43.13 KDa
Source organism: Thermoplasma acidophilum
Expression system: Escherichia coli
UniProt:
  • Canonical: P21553 (Residues: 1-385; Coverage: 100%)
Gene names: Ta0169, gltA
Sequence domains: Citrate synthase, C-terminal domain
Structure domains:

Ligands and Environments

1 bound ligand:
Ligand OAA 4 x OAA
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ALS BEAMLINE 4.2.2
Spacegroup: P21
Unit cell:
a: 78.526Å b: 97.447Å c: 106.937Å
α: 90° β: 93.1° γ: 90°
R-values:
R R work R free
0.183 0.181 0.234
Expression system: Escherichia coli

Quick links