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SHORT CHAIN SPECIFIC ACYL-COA OXIDASE FROM ARABIDOPSIS THALIANA, ACX4

Source organism: Arabidopsis thaliana
Biochemical function: salicylic acid binding
Biological process: short-chain fatty acid metabolic process
Cellular component: glyoxysome

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EC 1.3.3.6: Acyl-CoA oxidase

Reaction catalysed:
Acyl-CoA + O(2) = trans-2,3-dehydroacyl-CoA + H(2)O(2)
Systematic name:
Acyl-CoA:oxygen 2-oxidoreductase
Alternative Name(s):
  • Acyl coenzyme A oxidase
  • Fatty acyl-CoA oxidase
  • Fatty acyl-coenzyme A oxidase

GO terms

Sequence families

Pfam Protein families (Pfam)
PF00441
Domain description: Acyl-CoA dehydrogenase, C-terminal domain
Occurring in:
  1. Acyl-coenzyme A oxidase 4, peroxisomal
The deposited structure of PDB entry 2ix6 contains 6 copies of Pfam domain PF00441 (Acyl-CoA dehydrogenase, C-terminal domain) in Acyl-coenzyme A oxidase 4, peroxisomal. Showing 1 copy in chain A.

PF02770
Domain description: Acyl-CoA dehydrogenase, middle domain
Occurring in:
  1. Acyl-coenzyme A oxidase 4, peroxisomal
The deposited structure of PDB entry 2ix6 contains 6 copies of Pfam domain PF02770 (Acyl-CoA dehydrogenase, middle domain) in Acyl-coenzyme A oxidase 4, peroxisomal. Showing 1 copy in chain A.

PF02771
Domain description: Acyl-CoA dehydrogenase, N-terminal domain
Occurring in:
  1. Acyl-coenzyme A oxidase 4, peroxisomal
The deposited structure of PDB entry 2ix6 contains 6 copies of Pfam domain PF02771 (Acyl-CoA dehydrogenase, N-terminal domain) in Acyl-coenzyme A oxidase 4, peroxisomal. Showing 1 copy in chain A.

InterPro InterPro annotations
IPR006089
Domain description: Acyl-CoA dehydrogenase, conserved site
Occurring in:
  1. Acyl-coenzyme A oxidase 4, peroxisomal
IPR009075
Domain description: Acyl-CoA dehydrogenase/oxidase, C-terminal
Occurring in:
  1. Acyl-coenzyme A oxidase 4, peroxisomal
IPR036250
Domain description: Acyl-CoA dehydrogenase-like, C-terminal
Occurring in:
  1. Acyl-coenzyme A oxidase 4, peroxisomal
IPR006091
Domain description: Acyl-CoA oxidase/dehydrogenase, middle domain
Occurring in:
  1. Acyl-coenzyme A oxidase 4, peroxisomal
IPR046373
Domain description: Acyl-CoA oxidase/dehydrogenase, middle domain superfamily
Occurring in:
  1. Acyl-coenzyme A oxidase 4, peroxisomal
IPR013786
Domain description: Acyl-CoA dehydrogenase/oxidase, N-terminal
Occurring in:
  1. Acyl-coenzyme A oxidase 4, peroxisomal
IPR009100
Domain description: Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily
Occurring in:
  1. Acyl-coenzyme A oxidase 4, peroxisomal
IPR037069
Domain description: Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily
Occurring in:
  1. Acyl-coenzyme A oxidase 4, peroxisomal
IPR045008
Domain description: Acyl-coenzyme A oxidase 4-like
Occurring in:
  1. Acyl-coenzyme A oxidase 4, peroxisomal

Structure domains

CATH CATH domains
1.20.140.10
Class: Mainly Alpha
Architecture: Up-down Bundle
Topology: Butyryl-CoA Dehydrogenase, subunit A; domain 3
Homology: Butyryl-CoA Dehydrogenase, subunit A, domain 3
Occurring in:
  1. Acyl-coenzyme A oxidase 4, peroxisomal
The deposited structure of PDB entry 2ix6 contains 6 copies of CATH domain 1.20.140.10 (Butyryl-CoA Dehydrogenase, subunit A; domain 3) in Acyl-coenzyme A oxidase 4, peroxisomal. Showing 1 copy in chain A.
2.40.110.10
Class: Mainly Beta
Architecture: Beta Barrel
Topology: Butyryl-CoA Dehydrogenase, subunit A; domain 2
Homology: Butyryl-CoA Dehydrogenase, subunit A, domain 2
Occurring in:
  1. Acyl-coenzyme A oxidase 4, peroxisomal
The deposited structure of PDB entry 2ix6 contains 6 copies of CATH domain 2.40.110.10 (Butyryl-CoA Dehydrogenase, subunit A; domain 2) in Acyl-coenzyme A oxidase 4, peroxisomal. Showing 1 copy in chain A.
1.10.540.10
Class: Mainly Alpha
Architecture: Orthogonal Bundle
Topology: Butyryl-Coa Dehydrogenase, subunit A; domain 1
Homology: Acyl-CoA dehydrogenase/oxidase, N-terminal domain
Occurring in:
  1. Acyl-coenzyme A oxidase 4, peroxisomal
The deposited structure of PDB entry 2ix6 contains 6 copies of CATH domain 1.10.540.10 (Butyryl-Coa Dehydrogenase, subunit A; domain 1) in Acyl-coenzyme A oxidase 4, peroxisomal. Showing 1 copy in chain A.

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