› 2j1r

X-ray diffraction
1.54Å resolution

Structure of a Streptococcus pneumoniae fucose binding module

Released:
DOI: 10.2210/pdb2j1r/pdb
PDB entry 2j1r coloured by chain, front view.
PDB entry 2j1r coloured by chain, side view.
PDB entry 2j1r coloured by chain, top view.
Source organism: Streptococcus pneumoniae TIGR4
Primary publication:
Blood group antigen recognition by a Streptococcus pneumoniae virulence factor.
Boraston AB, Wang D, Burke RD
J Biol Chem 281 35263-71 (2006)
PMID: 16987809

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-101490 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
F5/8 type C domain-containing protein Chains: A, B
Molecule details ›
Chains: A, B
Length: 151 amino acids
Theoretical weight: 16.85 KDa
Source organism: Streptococcus pneumoniae TIGR4
Expression system: Escherichia coli
UniProt:
  • Canonical: A0A0H2US34 (Residues: 601-745; Coverage: 14%)
Gene name: SP_2159
Sequence domains: NedA-like, galactose-binding domain
Structure domains: Galactose-binding domain-like

Ligands and Environments

1 bound ligand:
Ligand CA 2 x CA
No modified residues

Experiments and Validation Details

Entry percentile scores
Spacegroup: P212121
Unit cell:
a: 43.581Å b: 60.39Å c: 99.674Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.156 0.154 0.198
Expression system: Escherichia coli

Quick links

Citations

5 review citations

Carbohydrate-binding domains: multiplicity of biological roles.
Guillén et al. (2010)
4 more

3 mentions without citation

Structure of the lectin regulatory domain of the cholesterol-dependent cytolysin lectinolysin reveals the basis for its lewis antigen specificity.
Feil et al. (2012)
2 more