› › Function and Biology

CRYSTAL STRUCTURE OF THE FILAMIN A REPEAT 21 COMPLEXED WITH THE INTEGRIN BETA2 CYTOPLASMIC TAIL PEPTIDE

Source organism: Homo sapiens
Biochemical function: actin filament binding
Biological process: actin cytoskeleton organization
Cellular component: not assigned

Quick links

GO terms

Biochemical function:
Biological process:
Cellular component:
  • not assigned

Sequence families

Pfam Protein families (Pfam)
PF08725
Domain description: Integrin beta cytoplasmic domain
Occurring in:
  1. Integrin beta-2
The deposited structure of PDB entry 2jf1 contains 1 copy of Pfam domain PF08725 (Integrin beta cytoplasmic domain) in Integrin beta-2. Showing 1 copy in chain B [auth T].

PF00630
Domain description: Filamin/ABP280 repeat
Occurring in:
  1. Filamin-A
The deposited structure of PDB entry 2jf1 contains 1 copy of Pfam domain PF00630 (Filamin/ABP280 repeat) in Filamin-A. Showing 1 copy in chain A.

InterPro InterPro annotations
IPR014836
Domain description: Integrin beta subunit, cytoplasmic domain
Occurring in:
  1. Integrin beta-2
IPR017868
Domain description: Filamin/ABP280 repeat-like
Occurring in:
  1. Filamin-A
IPR001298
Domain description: Filamin/ABP280 repeat
Occurring in:
  1. Filamin-A
IPR014756
Domain description: Immunoglobulin E-set
Occurring in:
  1. Filamin-A
IPR044801
Domain description: Filamin family
Occurring in:
  1. Filamin-A
IPR013783
Domain description: Immunoglobulin-like fold
Occurring in:
  1. Filamin-A

Structure domain

CATH CATH domain
2.60.40.10
Class: Mainly Beta
Architecture: Sandwich
Topology: Immunoglobulin-like
Homology: Immunoglobulins
Occurring in:
  1. Filamin-A
The deposited structure of PDB entry 2jf1 contains 1 copy of CATH domain 2.60.40.10 (Immunoglobulin-like) in Filamin-A. Showing 1 copy in chain A.
SCOP SCOP annotation
81290
Class: All beta proteins
Fold: Immunoglobulin-like beta-sandwich
Superfamily: E set domains
Occurring in:
  1. Filamin-A
The deposited structure of PDB entry 2jf1 contains 1 copy of SCOP domain 81290 (Filamin repeat (rod domain)) in Filamin-A. Showing 1 copy in chain A.

Quick links