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Solution NMR

The NMR Solution Structure of Recombinant RGD-hirudin

Released:
DOI: 10.2210/pdb2joo/pdb
PDB entry 2joo coloured by chain, ensemble of 20 models, front view.
PDB entry 2joo coloured by chain, ensemble of 20 models, side view.
PDB entry 2joo coloured by chain, ensemble of 20 models, top view.
Source organism: Hirudo medicinalis
Primary publication:
The NMR solution structure of recombinant RGD-hirudin.
Song X, Mo W, Liu X, Zhu L, Yan X, Song H, Dai L
Biochem Biophys Res Commun 360 103-8 (2007)
PMID: 17585879

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-133907 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Hirudin variant-1 Chain: A
Molecule details ›
Chain: A
Length: 66 amino acids
Theoretical weight: 7.04 KDa
Source organism: Hirudo medicinalis
Expression system: Komagataella pastoris
UniProt:
  • Canonical: P01050 (Residues: 1-65; Coverage: 100%)
Sequence domains: Hirudin
Structure domains: Thrombin Inhibitor (Hirudin), subunit I

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

wwPDB Validation report is not available for this NMR entry.
Refinement method: simulated annealing
Expression system: Komagataella pastoris

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Citations

1 review citation

Proton Bridging in Catalysis by and Inhibition of Serine Proteases of the Blood Cascade System.
Kovach IM. (2021)
5 other articles

3 mentions without citation

A new way to see RNA.
Keating et al. (2011)
2 more