› 2jtp

Solution NMR

Solution Structure of the Frameshift-Inducing RNA Stem-Loop in SIV

Released:
DOI: 10.2210/pdb2jtp/pdb
PDB entry 2jtp coloured by chain, ensemble of 20 models, front view.
PDB entry 2jtp coloured by chain, ensemble of 20 models, side view.
PDB entry 2jtp coloured by chain, ensemble of 20 models, top view.
Source organism: Synthetic construct
Primary publication:
Programmed ribosomal frameshifting in SIV is induced by a highly structured RNA stem-loop.
Marcheschi RJ, Staple DW, Butcher SE
J Mol Biol 373 652-63 (2007)
PMID: 17868691

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-196397 (preferred)
Entry contents:
1 distinct RNA molecule
Macromolecule:
SIV17-50 RNA (34-MER) Chain: A
Molecule details ›
Chain: A
Length: 34 nucleotides
Theoretical weight: 10.91 KDa
Source organism: Synthetic construct
Expression system: Not provided

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: simulated annealing, torsion angle dynamics, molecular dynamics, residual dipolar couplings
Expression system: Not provided

Quick links

Citations

6 review citations

Frameshifting RNA pseudoknots: structure and mechanism.
Giedroc et al. (2009)
5 more

5 mentions without citation

Stapled Peptides Inhibitors: A New Window for Target Drug Discovery.
Ali et al. (2019)
4 more