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Solution structure of Engrailed homeodomain WT

Source organism: Drosophila melanogaster
Biochemical function: DNA binding
Biological process: regulation of DNA-templated transcription
Cellular component: not assigned

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GO terms

Sequence family

Pfam Protein family (Pfam)
PF00046
Domain description: Homeodomain
Occurring in:
  1. Segmentation polarity homeobox protein engrailed
The deposited structure of PDB entry 2jwt contains 1 copy of Pfam domain PF00046 (Homeodomain) in Segmentation polarity homeobox protein engrailed. Showing 1 copy in chain A.

InterPro InterPro annotations
IPR001356
Domain description: Homeodomain
Occurring in:
  1. Segmentation polarity homeobox protein engrailed
IPR020479
Domain description: Homeodomain, metazoa
Occurring in:
  1. Segmentation polarity homeobox protein engrailed
IPR000047
Domain description: Helix-turn-helix motif
Occurring in:
  1. Segmentation polarity homeobox protein engrailed
IPR017970
Domain description: Homeobox, conserved site
Occurring in:
  1. Segmentation polarity homeobox protein engrailed
IPR009057
Domain description: Homedomain-like superfamily
Occurring in:
  1. Segmentation polarity homeobox protein engrailed

Structure domain

CATH CATH domain
1.10.10.60
Class: Mainly Alpha
Architecture: Orthogonal Bundle
Topology: Arc Repressor Mutant, subunit A
Homology: Homeodomain-like
Occurring in:
  1. Segmentation polarity homeobox protein engrailed
The deposited structure of PDB entry 2jwt contains 1 copy of CATH domain 1.10.10.60 (Arc Repressor Mutant, subunit A) in Segmentation polarity homeobox protein engrailed. Showing 1 copy in chain A.
SCOP SCOP annotation
46690
Class: All alpha proteins
Fold: DNA/RNA-binding 3-helical bundle
Superfamily: Homeodomain-like
Occurring in:
  1. Segmentation polarity homeobox protein engrailed
The deposited structure of PDB entry 2jwt contains 1 copy of SCOP domain 46690 (Homeodomain) in Segmentation polarity homeobox protein engrailed. Showing 1 copy in chain A.

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