› 2jwu

Solution NMR

Solution NMR structures of two designed proteins with 88% sequence identity but different fold and function

Released:
DOI: 10.2210/pdb2jwu/pdb
PDB entry 2jwu coloured by chain, ensemble of 20 models, front view.
PDB entry 2jwu coloured by chain, ensemble of 20 models, side view.
PDB entry 2jwu coloured by chain, ensemble of 20 models, top view.
Source organism: synthetic construct
Primary publication:
NMR structures of two designed proteins with high sequence identity but different fold and function.
He Y, Chen Y, Alexander P, Bryan PN, Orban J
Proc Natl Acad Sci U S A 105 14412-7 (2008)
PMID: 18796611

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-162801 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Gb88 Chain: A
Molecule details ›
Chain: A
Length: 56 amino acids
Theoretical weight: 6.46 KDa
Source organism: synthetic construct
Expression system: Escherichia coli BL21(DE3)
Structure domains: Ubiquitin-like (UB roll)

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

wwPDB Validation report is not available for this NMR entry.
Chemical shift assignment: 85%
Refinement method: simulated annealing
Expression system: Escherichia coli BL21(DE3)

Quick links

Citations

14 review citations

Proteins that switch folds.
Bryan et al. (2010)
13 more

10 mentions without citation

Recent Structural Insights into Cytochrome P450 Function.
Guengerich et al. (2016)
9 more