› 2jwv

Solution NMR

Structure of a high affinity anti-NFkB RNA aptamer

Released:
DOI: 10.2210/pdb2jwv/pdb
PDB entry 2jwv coloured by chain, ensemble of 10 models, front view.
PDB entry 2jwv coloured by chain, ensemble of 10 models, side view.
PDB entry 2jwv coloured by chain, ensemble of 10 models, top view.
Source organism: Synthetic construct
Primary publication:
DNA mimicry by a high-affinity anti-NF-kappaB RNA aptamer.
Reiter NJ, Maher LJ, Butcher SE
OpenAccess logo Nucleic Acids Res 36 1227-36 (2008)
PMID: 18160411

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-196399 (preferred)
Entry contents:
1 distinct RNA molecule
Macromolecule:
RNA (29-MER) Chain: A
Molecule details ›
Chain: A
Length: 29 nucleotides
Theoretical weight: 9.33 KDa
Source organism: Synthetic construct
Expression system: Not provided

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Chemical shift assignment: 84%
Refinement method: simulated annealing
Expression system: Not provided

Quick links

Citations

6 review citations

The structure, function and evolution of proteins that bind DNA and RNA.
Hudson et al. (2014)
5 more

10 mentions without citation

Structural Insights into Protein-Aptamer Recognitions Emerged from Experimental and Computational Studies.
Troisi et al. (2023)
9 more