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NMR structure of HESX-1 homeodomain double mutant R31L/E42L

Solution NMR
PDB entry 2k40 coloured by chain, ensemble of 20 models, front view.
PDB entry 2k40 coloured by chain, ensemble of 20 models, side view.
PDB entry 2k40 coloured by chain, ensemble of 20 models, top view.
Source organism: Homo sapiens
Assembly composition:
monomeric (preferred)
Entry contents: 1 distinct polypeptide molecule

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Assemblies

Assembly 1 (preferred)
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Assembly Name: Homeobox expressed in ES cells 1
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Multimeric state: monomeric
Accessible surface area: 5710.17 Å2
Buried surface area: 0.0 Å2
Dissociation area: 0 Å2
Dissociation energy (ΔGdiss): 0 kcal/mol
Dissociation entropy (TΔSdiss): 0 kcal/mol
Symmetry number: 1
PDBe Complex ID: PDB-CPX-577367

Macromolecules

Homeobox expressed in ES cells 1
Chain: A
Length: 67 amino acids
Theoretical weight: 8.13 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q9UBX0 (Residues: 108-174; Coverage: 36%)
Gene names: HANF, HESX1
Pfam: Homeodomain
InterPro:
CATH: Homeodomain-like
Homeobox expressed in ES cells 1 in PDB entry 2k40, assembly 1, front view.
Homeobox expressed in ES cells 1 in PDB entry 2k40, assembly 1, side view.
Homeobox expressed in ES cells 1 in PDB entry 2k40, assembly 1, top view.
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