› 2k7o

Solution NMR

Ca2+-S100B, refined with RDCs

Released:
DOI: 10.2210/pdb2k7o/pdb
PDB entry 2k7o coloured by chain, ensemble of 20 models, front view.
PDB entry 2k7o coloured by chain, ensemble of 20 models, side view.
PDB entry 2k7o coloured by chain, ensemble of 20 models, top view.
Source organism: Rattus norvegicus
Primary publication:
Refinement of the solution structure and dynamic properties of Ca(2+)-bound rat S100B.
Wright NT, Inman KG, Levine JA, Cannon BR, Varney KM, Weber DJ
J Biomol NMR 42 279-86 (2008)
PMID: 18949447

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-528723 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Protein S100-B Chains: A, B
Molecule details ›
Chains: A, B
Length: 91 amino acids
Theoretical weight: 10.63 KDa
Source organism: Rattus norvegicus
Expression system: Escherichia coli
UniProt:
  • Canonical: P04631 (Residues: 2-92; Coverage: 99%)
Gene name: S100b
Sequence domains:
Structure domains: EF-hand

Ligands and Environments

1 bound ligand:
Ligand CA 4 x CA
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: simulated annealing
Expression system: Escherichia coli

Quick links

Citations

2 review citations

Clinical applications of biomarkers in pediatric traumatic brain injury.
Sandler et al. (2010)
1 more

9 mentions without citation

The effects of CapZ peptide (TRTK-12) binding to S100B-Ca2+ as examined by NMR and X-ray crystallography.
Charpentier et al. (2010)
8 more