› 2k8d

Solution NMR

Solution structure of a zinc-binding methionine sulfoxide reductase

Released:
DOI: 10.2210/pdb2k8d/pdb
PDB entry 2k8d coloured by chain, ensemble of 20 models, front view.
PDB entry 2k8d coloured by chain, ensemble of 20 models, side view.
PDB entry 2k8d coloured by chain, ensemble of 20 models, top view.
Source organism: Methanothermobacter thermautotrophicus str. Delta H
Primary publication:
Structure-function relationship in an archaebacterial methionine sulphoxide reductase B.
Carella M, Becher J, Ohlenschläger O, Ramachandran R, Gührs KH, Wellenreuther G, Meyer-Klaucke W, Heinemann SH, Görlach M
Mol Microbiol 79 342-58 (2011)
PMID: 21219456

Function and Biology Details

Reaction catalysed: 
Peptide-L-methionine + thioredoxin disulfide + H(2)O = peptide-L-methionine (R)-S-oxide + thioredoxin
Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-127860 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Peptide methionine sulfoxide reductase MsrB Chain: A
Molecule details ›
Chain: A
Length: 151 amino acids
Theoretical weight: 17.33 KDa
Source organism: Methanothermobacter thermautotrophicus str. Delta H
Expression system: Escherichia coli
UniProt:
  • Canonical: O26807 (Residues: 1-151; Coverage: 100%)
Gene names: MTH_711, msrB
Sequence domains: SelR domain
Structure domains: Peptide methionine sulfoxide reductase.

Ligands and Environments

1 bound ligand:
Ligand ZN 1 x ZN
No modified residues

Experiments and Validation Details

wwPDB Validation report is not available for this NMR entry.
Refinement method: DGSA-distance geometry simulated annealing, energy minimisation
Expression system: Escherichia coli

Quick links

Citations

1 review citation

Recharging oxidative protein repair: catalysis by methionine sulfoxide reductases towards their amino acid, protein, and model substrates.
Tarrago et al. (2012)
1 other article

3 mentions without citation

Methionine Sulfoxide Reductases of Archaea.
Maupin-Furlow JA. (2018)
2 more