› 2kc0

Solution NMR

Solution structure of the factor H binding protein

Released:
DOI: 10.2210/pdb2kc0/pdb
PDB entry 2kc0 coloured by chain, ensemble of 25 models, front view.
PDB entry 2kc0 coloured by chain, ensemble of 25 models, side view.
PDB entry 2kc0 coloured by chain, ensemble of 25 models, top view.
Source organism: Neisseria meningitidis
Primary publication:
Solution structure of the factor H-binding protein, a survival factor and protective antigen of Neisseria meningitidis.
Cantini F, Veggi D, Dragonetti S, Savino S, Scarselli M, Romagnoli G, Pizza M, Banci L, Rappuoli R
J Biol Chem 284 9022-6 (2009)
PMID: 19196709

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-180250 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Lipoprotein GNA1870 Chain: A
Molecule details ›
Chain: A
Length: 255 amino acids
Theoretical weight: 27.46 KDa
Source organism: Neisseria meningitidis
Expression system: Escherichia coli
UniProt:
  • Canonical: Q6QCC2 (Residues: 27-274; Coverage: 97%)
Gene names: fhbp, gna1870
Sequence domains:
Structure domains:

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: torsion angle dynamics, simulated annealing
Expression system: Escherichia coli

Quick links

Citations

15 review citations

Lipoproteins of bacterial pathogens.
Kovacs-Simon et al. (2011)
14 more

4 mentions without citation

The new multicomponent vaccine against meningococcal serogroup B, 4CMenB: immunological, functional and structural characterization of the antigens.
Serruto et al. (2012)
3 more