2ked

Solution NMR

Structure of SDF-1/CXCL12

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
monomeric (preferred)
PDBe Complex ID:
PDB-CPX-155703 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Stromal cell-derived factor 1 Chain: A
Molecule details ›
Chain: A
Length: 70 amino acids
Theoretical weight: 8.17 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P48061 (Residues: 22-89; Coverage: 94%)
Gene names: CXCL12, SDF1, SDF1A, SDF1B
Sequence domains: Small cytokines (intecrine/chemokine), interleukin-8 like
Structure domains: OB fold (Dihydrolipoamide Acetyltransferase, E2P)

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Chemical shift assignment: 90%
Refinement method: molecular dynamics
Expression system: Escherichia coli