Function and Biology

Mouse Prion Protein (121-231) with Mutations Y225A and Y226A

Source organism: Mus musculus
Biochemical function: not assigned
Biological process: protein homooligomerization
Cellular component: membrane

GO terms

Biochemical function:
  • not assigned
Biological process:
Cellular component:

Sequence family

Pfam Protein family (Pfam)
PF00377
Domain description: Prion/Doppel alpha-helical domain
Occurring in:
  1. Major prion protein
The deposited structure of PDB entry 2kfm contains 1 copy of Pfam domain PF00377 (Prion/Doppel alpha-helical domain) in Major prion protein. Showing 1 copy in chain A.

InterPro InterPro annotations
IPR022416
Domain description: Prion/Doppel protein, beta-ribbon domain
Occurring in:
  1. Major prion protein
IPR036924
Domain description: Prion/Doppel beta-ribbon domain superfamily
Occurring in:
  1. Major prion protein
IPR000817
Domain description: Prion protein
Occurring in:
  1. Major prion protein

Structure domain

CATH CATH domain
1.10.790.10
Class: Mainly Alpha
Architecture: Orthogonal Bundle
Topology: Major Prion Protein
Homology: Prion/Doppel protein, beta-ribbon domain
Occurring in:
  1. Major prion protein
The deposited structure of PDB entry 2kfm contains 1 copy of CATH domain 1.10.790.10 (Major Prion Protein) in Major prion protein. Showing 1 copy in chain A.