› 2kg0

Solution NMR

Structure of the second qRRM domain of hnRNP F in complex with a AGGGAU G-tract RNA

Released:
DOI: 10.2210/pdb2kg0/pdb
PDB entry 2kg0 coloured by chain, ensemble of 20 models, front view.
PDB entry 2kg0 coloured by chain, ensemble of 20 models, side view.
PDB entry 2kg0 coloured by chain, ensemble of 20 models, top view.
Source organism: Homo sapiens
Primary publication:
Structural basis of G-tract recognition and encaging by hnRNP F quasi-RRMs.
Dominguez C, Fisette JF, Chabot B, Allain FH
Nat Struct Mol Biol 17 853-61 (2010)
PMID: 20526337

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-546938 (preferred)
Entry contents:
1 distinct polypeptide molecule
1 distinct RNA molecule
Macromolecules (2 distinct):
Heterogeneous nuclear ribonucleoprotein F, N-terminally processed Chain: A
Molecule details ›
Chain: A
Length: 126 amino acids
Theoretical weight: 13.78 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21
UniProt:
  • Canonical: P52597 (Residues: 103-194; Coverage: 22%)
Gene names: HNRNPF, HNRPF
Sequence domains: RNA recognition motif
Structure domains: Alpha-Beta Plaits
5'-R(*AP*GP*GP*GP*AP*U)-3' Chain: B
Molecule details ›
Chain: B
Length: 6 nucleotides
Theoretical weight: 1.96 KDa
Source organism: Homo sapiens
Expression system: Not provided

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: simulated annealing
Expression systems:
  • Escherichia coli BL21
  • Not provided

Quick links

Citations

23 review citations

The hnRNP family: insights into their role in health and disease.
Geuens et al. (2016)
22 more

4 mentions without citation

The Repurposing of Cellular Proteins during Enterovirus A71 Infection.
Abedeera et al. (2023)
3 more