› 2kgs

Solution NMR

Solution structure of the amino-terminal domain of OmpATb, a pore forming protein from Mycobacterium tuberculosis

Released:
DOI: 10.2210/pdb2kgs/pdb
PDB entry 2kgs coloured by chain, ensemble of 10 models, front view.
PDB entry 2kgs coloured by chain, ensemble of 10 models, side view.
PDB entry 2kgs coloured by chain, ensemble of 10 models, top view.
Source organism: Mycobacterium tuberculosis
Primary publication:
Structure of the Mycobacterium tuberculosis OmpATb protein: a model of an oligomeric channel in the mycobacterial cell wall.
Yang Y, Auguin D, Delbecq S, Dumas E, Molle G, Molle V, Roumestand C, Saint N
Proteins 79 645-61 (2011)
PMID: 21117233

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-161661 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Peptidoglycan-binding protein ArfA Chain: A
Molecule details ›
Chain: A
Length: 132 amino acids
Theoretical weight: 13.61 KDa
Source organism: Mycobacterium tuberculosis
Expression system: Escherichia coli
UniProt:
  • Canonical: P9WIU5 (Residues: 73-204; Coverage: 41%)
Gene names: MTCY31.27, Rv0899, arfA, ompA
Sequence domains:
Structure domains: hypothetical protein tt1634

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Chemical shift assignment: 74%
Refinement method: DGSA-distance geometry simulated annealing, minimization
Expression system: Escherichia coli

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Citations

1 review citation

Antibacterial photodynamic therapy: overview of a promising approach to fight antibiotic-resistant bacterial infections.
Liu et al. (2015)
10 other articles

1 mention without citation

Solution NMR Studies of Mycobacterium tuberculosis Proteins for Antibiotic Target Discovery.
Kim et al. (2017)