› 2kh4

Solution NMR

Aflatoxin Formamidopyrimidine alpha anomer in single strand DNA

Released:
DOI: 10.2210/pdb2kh4/pdb
PDB entry 2kh4 coloured by chain, ensemble of 8 models, front view.
PDB entry 2kh4 coloured by chain, ensemble of 8 models, side view.
PDB entry 2kh4 coloured by chain, ensemble of 8 models, top view.
Source organism: Synthetic construct
Primary publication:
Structural perturbations induced by the alpha-anomer of the aflatoxin B(1) formamidopyrimidine adduct in duplex and single-strand DNA.
Brown KL, Voehler MW, Magee SM, Harris CM, Harris TM, Stone MP
OpenAccess logo J Am Chem Soc 131 16096-107 (2009)
PMID: 19831353

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-115480 (preferred)
Entry contents:
1 distinct DNA molecule
Macromolecule:
5'-D(*CP*TP*(FAG)P*A)-3' Chain: A
Molecule details ›
Chain: A
Length: 4 nucleotides
Theoretical weight: 1.54 KDa
Source organism: Synthetic construct
Expression system: Not provided

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Chemical shift assignment: 41%
Refinement method: molecular dynamics
Expression system: Not provided

Quick links

Citations

3 review citations

Structure-based DNA-targeting strategies with small molecule ligands for drug discovery.
Sheng et al. (2013)
2 more

1 mention without citation

Structural perturbations induced by the alpha-anomer of the aflatoxin B(1) formamidopyrimidine adduct in duplex and single-strand DNA.
Brown et al. (2009)