› 2kur

Solution NMR

Solution Structure of K10 TLS RNA (AU mutant in upper helix)

Released:
DOI: 10.2210/pdb2kur/pdb
PDB entry 2kur coloured by chain, ensemble of 10 models, front view.
PDB entry 2kur coloured by chain, ensemble of 10 models, side view.
PDB entry 2kur coloured by chain, ensemble of 10 models, top view.
Source organism: Drosophila melanogaster
Primary publication:
A'-form RNA helices are required for cytoplasmic mRNA transport in Drosophila.
Bullock SL, Ringel I, Ish-Horowicz D, Lukavsky PJ
OpenAccess logo Nat Struct Mol Biol 17 703-9 (2010)
PMID: 20473315

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-195860 (preferred)
Entry contents:
1 distinct RNA molecule
Macromolecule:
K10 TLS RNA Chain: A
Molecule details ›
Chain: A
Length: 48 nucleotides
Theoretical weight: 15.26 KDa
Source organism: Drosophila melanogaster
Expression system: Not provided
Sequence domains: K10 transport/localisation element (TLS)

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: simulated annealing, restrained molecular dynamics with RDCs
Expression system: Not provided

Quick links

Citations

23 review citations

Understanding the transcriptome through RNA structure.
Wan et al. (2011)
22 more

1 mention without citation

A'-form RNA helices are required for cytoplasmic mRNA transport in Drosophila.
Bullock et al. (2010)