Function and Biology Details
Biochemical function:
Biological process:
Cellular component:
- not assigned
Sequence domains:
Structure analysis Details
Assembly composition:
hetero dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-127258 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
cAMP-dependent protein kinase inhibitor alpha
Molecule details ›
Chain: A
Length: 27 amino acids
Theoretical weight: 2.75 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
Sequence domains: cAMP-dependent protein kinase inhibitor
Length: 27 amino acids
Theoretical weight: 2.75 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
- Canonical:
P61925 (Residues: 30-54; Coverage: 33%)
Sequence domains: cAMP-dependent protein kinase inhibitor
Exportin-1
Molecule details ›
Chain: B
Length: 127 amino acids
Theoretical weight: 14.81 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
Sequence domains: CRM1 / Exportin repeat 3
Structure domains: de novo design (two linked rop proteins)
Length: 127 amino acids
Theoretical weight: 14.81 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
- Canonical: O14980 (Residues: 504-630; Coverage: 12%)
Sequence domains: CRM1 / Exportin repeat 3
Structure domains: de novo design (two linked rop proteins)
Ligands and Environments
No bound ligands
No modified residues
Experiments and Validation Details
wwPDB Validation report is not available for this NMR entry.
Refinement method:
simulated annealing
Expression system: Escherichia coli
