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Solution NMR Structure of Med25(391-543) Comprising the Activator-Interacting Domain (ACID) of Human Mediator Subuniti 25. Northeast Structural Genomics Consortium Target HR6188A

Source organism: Homo sapiens
Biochemical function: not assigned
Biological process: not assigned
Cellular component: not assigned

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GO terms

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Sequence family

Pfam Protein family (Pfam)
PF11232
Domain description: Mediator complex subunit 25 PTOV activation and synapsin 2
Occurring in:
  1. Mediator of RNA polymerase II transcription subunit 25
The deposited structure of PDB entry 2l6u contains 1 copy of Pfam domain PF11232 (Mediator complex subunit 25 PTOV activation and synapsin 2) in Mediator of RNA polymerase II transcription subunit 25. Showing 1 copy in chain A.

InterPro InterPro annotations
IPR021394
Domain description: Mediator complex, subunit Med25, PTOV domain
Occurring in:
  1. Mediator of RNA polymerase II transcription subunit 25
IPR045105
Domain description: Med25/PTOV1
Occurring in:
  1. Mediator of RNA polymerase II transcription subunit 25
IPR038196
Domain description: Mediator complex subunit 25, PTOV domain superfamily
Occurring in:
  1. Mediator of RNA polymerase II transcription subunit 25

Structure domain

CATH CATH domain
2.40.290.30
Class: Mainly Beta
Architecture: Beta Barrel
Topology: Ku70; Chain: A; Domain 2
Homology: Mediator complex subunit 25, ACID domain
Occurring in:
  1. Mediator of RNA polymerase II transcription subunit 25
The deposited structure of PDB entry 2l6u contains 1 copy of CATH domain 2.40.290.30 (Ku70; Chain: A; Domain 2) in Mediator of RNA polymerase II transcription subunit 25. Showing 1 copy in chain A.

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