› 2lkk

Solution NMR

Human L-FABP in complex with oleate

Released:
DOI: 10.2210/pdb2lkk/pdb
PDB entry 2lkk coloured by chain, ensemble of 10 models, front view.
PDB entry 2lkk coloured by chain, ensemble of 10 models, side view.
PDB entry 2lkk coloured by chain, ensemble of 10 models, top view.
Source organism: Homo sapiens
Primary publication:
Solution structure and backbone dynamics of human liver fatty acid binding protein: fatty acid binding revisited.
Cai J, Lücke C, Chen Z, Qiao Y, Klimtchuk E, Hamilton JA
Biophys J 102 2585-94 (2012)
PMID: 22713574

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-139399 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Fatty acid-binding protein, liver Chain: A
Molecule details ›
Chain: A
Length: 126 amino acids
Theoretical weight: 14.1 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P07148 (Residues: 2-127; Coverage: 99%)
Gene names: FABP1, FABPL
Sequence domains: Lipocalin / cytosolic fatty-acid binding protein family
Structure domains: Lipocalin

Ligands and Environments

1 bound ligand:
Ligand OLA 2 x OLA
No modified residues

Experiments and Validation Details

wwPDB Validation report is not available for this NMR entry.
Chemical shift assignment: 58%
Refinement method: molecular dynamics
Expression system: Escherichia coli

Quick links

Citations

5 review citations

L-FABP: A novel biomarker of kidney disease.
Xu et al. (2015)
4 more

5 mentions without citation

Lipocalin 2 (LCN2) Expression in Hepatic Malfunction and Therapy.
Asimakopoulou et al. (2016)
4 more