Function and Biology Details
Reactions catalysed:
Nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1)
Endopeptidase with a preference for cleavage when the P1 position is occupied by Glu-|- and the P1' position is occupied by Gly-|-
NTP + H(2)O = NDP + phosphate
Biochemical function:
Biological process:
Cellular component:
- not assigned
Sequence domain:
Structure analysis Details
Assembly composition:
monomeric (preferred)
Assembly name:
Viral genome-linked protein (preferred)
PDBe Complex ID:
PDB-CPX-182353 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Viral genome-linked protein
Molecule details ›
Chain: A
Length: 75 amino acids
Theoretical weight: 8.88 KDa
Source organism: Murine norovirus 1
Expression system: Escherichia coli BL21(DE3)
UniProt:
Structure domains: Arc Repressor Mutant, subunit A
Length: 75 amino acids
Theoretical weight: 8.88 KDa
Source organism: Murine norovirus 1
Expression system: Escherichia coli BL21(DE3)
UniProt:
- Canonical:
Q80J95 (Residues: 881-955; Coverage: 4%)
Structure domains: Arc Repressor Mutant, subunit A
Ligands and Environments
No bound ligands
No modified residues
Experiments and Validation Details
Chemical shift assignment:
88%
Refinement method:
simulated annealing
Expression system: Escherichia coli BL21(DE3)
