› 2me0

Solution NMR

NMR Structure of the homeodomain transcription factor Gbx1 from Homo sapiens solved in the presence of the DNA sequence CGACTAATTAGTCG

Released:
DOI: 10.2210/pdb2me0/pdb
PDB entry 2me0 coloured by chain, ensemble of 20 models, front view.
PDB entry 2me0 coloured by chain, ensemble of 20 models, side view.
PDB entry 2me0 coloured by chain, ensemble of 20 models, top view.
Source organism: Homo sapiens
Entry authors: Proudfoot A, Serrano P, Geralt M, Wuthrich K, Joint Center for Structural Genomics (JCSG), Partnership for Stem Cell Biology (STEMCELL)

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-556457 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Homeobox protein GBX-1 Chain: A
Molecule details ›
Chain: A
Length: 71 amino acids
Theoretical weight: 8.35 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q14549 (Residues: 256-325; Coverage: 19%)
Gene name: GBX1
Sequence domains: Homeodomain
Structure domains: Homeodomain-like

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Chemical shift assignment: 84%
Refinement method: molecular dynamics
Expression system: Escherichia coli

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