2mh2

Solution NMR

Structural insights into the DNA recognition and protein interaction domains reveal fundamental homologous DNA pairing properties of HOP2

Released:

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
PDBe Complex ID:
PDB-CPX-128647 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Homologous-pairing protein 2 homolog Chain: A
Molecule details ›
Chain: A
Length: 84 amino acids
Theoretical weight: 9.26 KDa
Source organism: Mus musculus
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: O35047 (Residues: 1-84; Coverage: 39%)
Gene names: Hop2, Psmc3ip, Tbpip
Sequence domains: TBPIP/Hop2 winged helix domain
Structure domains: Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Chemical shift assignment: 82%
Refinement method: distance geometry
Expression system: Escherichia coli BL21(DE3)