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Solution NMR

Solution Structures of Active Ptr ToxB and its inactive Homolog highlight Protein Dynamics as a Modulator of Toxin activity.

Released:
DOI: 10.2210/pdb2mm2/pdb
PDB entry 2mm2 coloured by chain, ensemble of 20 models, front view.
PDB entry 2mm2 coloured by chain, ensemble of 20 models, side view.
PDB entry 2mm2 coloured by chain, ensemble of 20 models, top view.
Source organism: Pyrenophora tritici-repentis
Primary publication:
Solution NMR structures of Pyrenophora tritici-repentis ToxB and its inactive homolog reveal potential determinants of toxin activity.
Nyarko A, Singarapu KK, Figueroa M, Manning VA, Pandelova I, Wolpert TJ, Ciuffetti LM, Barbar E
J Biol Chem 289 25946-56 (2014)
PMID: 25063993

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-184985 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
ToxB-like N-terminal ascomycota domain-containing protein Chain: A
Molecule details ›
Chain: A
Length: 65 amino acids
Theoretical weight: 6.62 KDa
Source organism: Pyrenophora tritici-repentis
Expression system: Komagataella pastoris
UniProt:
  • Canonical: Q8J0U6 (Residues: 24-88; Coverage: 100%)
Gene name: toxb
Sequence domains: ToxB N-terminal domain
Structure domains: Complement Module; domain 1

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Chemical shift assignment: 87%
Refinement method: simulated annealing
Expression system: Komagataella pastoris

Quick links

Citations

1 review citation

Lessons in Effector and NLR Biology of Plant-Microbe Systems.
Białas et al. (2018)
16 other articles

4 mentions without citation

Effectors of Filamentous Plant Pathogens: Commonalities amid Diversity.
Franceschetti et al. (2017)
3 more