› 2mrz

Solution NMR

Dimeric structure of the Human A-box

Released:
DOI: 10.2210/pdb2mrz/pdb
PDB entry 2mrz coloured by chain, ensemble of 10 models, front view.
PDB entry 2mrz coloured by chain, ensemble of 10 models, side view.
PDB entry 2mrz coloured by chain, ensemble of 10 models, top view.
Source organism: synthetic construct
Primary publication:
Centromeric Alpha-Satellite DNA Adopts Dimeric i-Motif Structures Capped by AT Hoogsteen Base Pairs.
Garavís M, Escaja N, Gabelica V, Villasante A, González C
Chemistry 21 9816-24 (2015)
PMID: 26013031

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-115640 (preferred)
Entry contents:
1 distinct DNA molecule
Macromolecule:
DNA (5'-D(P*TP*CP*CP*TP*TP*TP*TP*CP*CP*A)-3') Chains: A, B
Molecule details ›
Chains: A, B
Length: 10 nucleotides
Theoretical weight: 2.95 KDa
Source organism: synthetic construct
Expression system: Not provided

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Chemical shift assignment: 22%
Refinement method: molecular dynamics
Expression system: Not provided

Quick links

Citations

6 review citations

Sequence, Chromatin and Evolution of Satellite DNA.
Thakur et al. (2021)
5 more

3 mentions without citation

Chiral Systems Made from DNA.
Winogradoff et al. (2021)
2 more