› 2muh

Solution NMR

High-resolution NMR structure of the protegrin-2 docked to DPC Micelles

Released:
DOI: 10.2210/pdb2muh/pdb
PDB entry 2muh coloured by chain, ensemble of 20 models, front view.
PDB entry 2muh coloured by chain, ensemble of 20 models, side view.
PDB entry 2muh coloured by chain, ensemble of 20 models, top view.
Source organism: Sus scrofa
Primary publication:
High-resolution NMR structure of the antimicrobial peptide protegrin-2 in the presence of DPC micelles.
Usachev KS, Efimov SV, Kolosova OA, Filippov AV, Klochkov VV
J Biomol NMR 61 227-34 (2015)
PMID: 25430060

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-152228 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Protegrin-2 Chain: A
Molecule details ›
Chain: A
Length: 16 amino acids
Theoretical weight: 1.95 KDa
Source organism: Sus scrofa
Expression system: Not provided
UniProt:
  • Canonical: P32195 (Residues: 131-146; Coverage: 14%)
Gene name: NPG2

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Chemical shift assignment: 46%
Refinement method: simulated annealing
Expression system: Not provided

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Citations

3 review citations

Perturbations of Native Membrane Protein Structure in Alkyl Phosphocholine Detergents: A Critical Assessment of NMR and Biophysical Studies.
Chipot et al. (2018)
2 more

4 mentions without citation

High-resolution NMR structure of the antimicrobial peptide protegrin-2 in the presence of DPC micelles.
Usachev et al. (2015)
3 more