› 2mvo

Solution NMR

Solution structure of the lantibiotic self-resistance lipoprotein MlbQ from Microbispora ATCC PTA-5024

Released:
DOI: 10.2210/pdb2mvo/pdb
PDB entry 2mvo coloured by chain, ensemble of 20 models, front view.
PDB entry 2mvo coloured by chain, ensemble of 20 models, side view.
PDB entry 2mvo coloured by chain, ensemble of 20 models, top view.
Source organism: Microbispora sp. ATCC PTA-5024
Primary publication:
Distinct mechanisms contribute to immunity in the lantibiotic NAI-107 producer strain Microbispora ATCC PTA-5024.
Pozzi R, Coles M, Linke D, Kulik A, Nega M, Wohlleben W, Stegmann E
Environ Microbiol 18 118-32 (2016)
PMID: 25923468

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-197729 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Putative lipoprotein Chain: A
Molecule details ›
Chain: A
Length: 147 amino acids
Theoretical weight: 15.46 KDa
Source organism: Microbispora sp. ATCC PTA-5024
Expression system: Escherichia coli
UniProt:
  • Canonical: W2EQT0 (Residues: 37-141; Coverage: 75%)
Gene names: MPTA5024_21425, mlbQ
Sequence domains: Protein of unknown function (DUF2511)

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

wwPDB Validation report is not available for this NMR entry.
Chemical shift assignment: 89%
Refinement method: simulated annealing, NOESY back-calculation
Expression system: Escherichia coli

Quick links

Citations

3 review citations

Antibiotic Resistance Mechanisms in Bacteria: Relationships Between Resistance Determinants of Antibiotic Producers, Environmental Bacteria, and Clinical Pathogens.
Peterson et al. (2018)
2 more

2 mentions without citation

Mechanistic Understanding of Lanthipeptide Biosynthetic Enzymes.
Repka et al. (2017)
1 more