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An arsenate reductase in the phosphate binding state

Source organism: Synechocystis sp. PCC 6803 substr. Kazusa
Biochemical function: hydrolase activity
Biological process: response to arsenic-containing substance
Cellular component: not assigned

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EC 3.1.3.48: Protein-tyrosine-phosphatase

Reaction catalysed:
Protein tyrosine phosphate + H(2)O = protein tyrosine + phosphate
Systematic name:
Protein-tyrosine-phosphate phosphohydrolase
Alternative Name(s):
  • (Phosphotyrosine)protein phosphatase
  • PPT-phosphatase
  • PTP-phosphatase
  • PTPase
  • Phosphoprotein phosphatase (phosphotyrosine)
  • Phosphotyrosine histone phosphatase
  • Phosphotyrosine phosphatase
  • Phosphotyrosine protein phosphatase
  • Phosphotyrosylprotein phosphatase
  • Protein phosphotyrosine phosphatase
  • Tyrosine O-phosphate phosphatase
  • Tyrosylprotein phosphatase

EC 1.20.4.1: Arsenate reductase (glutathione/glutaredoxin)

Reaction catalysed:
Arsenate + glutathione + glutaredoxin = arsenite + a glutaredoxin-glutathione disulfide + H(2)O
Systematic name:
Arsenate:glutathione/glutaredoxin oxidoreductase
Alternative Name(s):
  • ArsC
  • Arsenate reductase (glutaredoxin)
  • Arsenate:glutaredoxin oxidoreductase

GO terms

Sequence family

Pfam Protein family (Pfam)
PF01451
Domain description: Low molecular weight phosphotyrosine protein phosphatase
Occurring in:
  1. Glutaredoxin arsenate reductase
The deposited structure of PDB entry 2myp contains 1 copy of Pfam domain PF01451 (Low molecular weight phosphotyrosine protein phosphatase) in Glutaredoxin arsenate reductase. Showing 1 copy in chain A.

InterPro InterPro annotations
IPR023485
Domain description: Phosphotyrosine protein phosphatase I
Occurring in:
  1. Glutaredoxin arsenate reductase
IPR014062
Domain description: Arsenate reductase, glutathione/glutaredoxin type
Occurring in:
  1. Glutaredoxin arsenate reductase
IPR036196
Domain description: Phosphotyrosine protein phosphatase I superfamily
Occurring in:
  1. Glutaredoxin arsenate reductase

Structure domain

CATH CATH domain
3.40.50.2300
Class: Alpha Beta
Architecture: 3-Layer(aba) Sandwich
Topology: Rossmann fold
Homology: Rossmann fold
Occurring in:
  1. Glutaredoxin arsenate reductase
The deposited structure of PDB entry 2myp contains 1 copy of CATH domain 3.40.50.2300 (Rossmann fold) in Glutaredoxin arsenate reductase. Showing 1 copy in chain A.

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