› 2n8l

Solution NMR

Zipcode-binding-protein-1 KH3KH4(DD) domains in complex with the KH3 RNA target

Released:
DOI: 10.2210/pdb2n8l/pdb
PDB entry 2n8l coloured by chain, ensemble of 12 models, front view.
PDB entry 2n8l coloured by chain, ensemble of 12 models, side view.
PDB entry 2n8l coloured by chain, ensemble of 12 models, top view.
Source organisms:
Entry authors: Nicastro G, Candel AM, Ramos A, Hollingworth D

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-519879 (preferred)
Entry contents:
1 distinct polypeptide molecule
1 distinct RNA molecule
Macromolecules (2 distinct):
Insulin-like growth factor 2 mRNA-binding protein 1 Chain: A
Molecule details ›
Chain: A
Length: 191 amino acids
Theoretical weight: 20.69 KDa
Source organism: Gallus gallus
Expression system: Escherichia coli
UniProt:
  • Canonical: O42254 (Residues: 387-573; Coverage: 33%)
Gene names: IGF2BP1, VICKZ1, ZBP1
Sequence domains: KH domain
Structure domains: TATA-Binding Protein
RNA (5'-R(P*GP*CP*AP*CP*AP*CP*CP*C)-3') Chain: B
Molecule details ›
Chain: B
Length: 8 nucleotides
Theoretical weight: 2.48 KDa
Source organism: synthetic construct
Expression system: Not provided

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Chemical shift assignment: 58%
Refinement method: torsion angle dynamics
Expression systems:
  • Escherichia coli
  • Not provided

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