› 2n95

Solution NMR

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-545921 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Protein HIT1 Chain: A
Molecule details ›
Chain: A
Length: 49 amino acids
Theoretical weight: 5.4 KDa
Source organism: Saccharomyces cerevisiae S288C
Expression system: Escherichia coli
UniProt:
  • Canonical: P46973 (Residues: 1-46; Coverage: 28%)
Gene names: HIT1, J1705, YJR055W
Sequence domains: HIT zinc finger

Ligands and Environments

1 bound ligand:
Ligand ZN 2 x ZN
No modified residues

Experiments and Validation Details

Entry percentile scores
Chemical shift assignment: 90%
Refinement method: simulated annealing
Expression system: Escherichia coli

Quick links

Citations

4 review citations

Assembly and trafficking of box C/D and H/ACA snoRNPs.
Massenet et al. (2017)
3 more

1 mention without citation

Studies of mutations of assembly factor Hit1 in budding yeast suggest translation defects as the molecular basis for PEHO syndrome.
Dreggors-Walker et al. (2022)