› 2nb8

Solution NMR

Solution structure of C-terminal extramembrane domain of SH protein

Released:
DOI: 10.2210/pdb2nb8/pdb
PDB entry 2nb8 coloured by chain, ensemble of 20 models, front view.
PDB entry 2nb8 coloured by chain, ensemble of 20 models, side view.
PDB entry 2nb8 coloured by chain, ensemble of 20 models, top view.
Source organism: Human respiratory syncytial virus A2
Primary publication:
Inhibition of the human respiratory syncytial virus small hydrophobic protein and structural variations in a bicelle environment.
Li Y, To J, Verdià-Baguena C, Dossena S, Surya W, Huang M, Paulmichl M, Liu DX, Aguilella VM, Torres J
J Virol 88 11899-914 (2014)
PMID: 25100835

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-534152 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Small hydrophobic protein Chain: A
Molecule details ›
Chain: A
Length: 27 amino acids
Theoretical weight: 3.21 KDa
Source organism: Human respiratory syncytial virus A2
Expression system: Escherichia coli
UniProt:
  • Canonical: P0DOE5 (Residues: 38-64; Coverage: 42%)
Gene names: 1A, SH
Sequence domains: Small hydrophobic protein

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Chemical shift assignment: 82%
Refinement method: simulated annealing
Expression system: Escherichia coli

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Citations

14 review citations

Coronavirus envelope protein: current knowledge.
Schoeman et al. (2019)
13 more