› 2nc8

Solution NMR

NMR structure of the Mycobacterium tuberculosis LppM (Rv2171) protein folded domain

Released:
DOI: 10.2210/pdb2nc8/pdb
PDB entry 2nc8 coloured by chain, ensemble of 30 models, front view.
PDB entry 2nc8 coloured by chain, ensemble of 30 models, side view.
PDB entry 2nc8 coloured by chain, ensemble of 30 models, top view.
Source organism: Mycobacterium tuberculosis
Primary publication:
Mycobacterium tuberculosis LppM Displays an Original Structure and Domain Composition Linked to a Dual Localization.
Barthe P, Veyron-Churlet R, de Visch A, Gilleron M, Saliou JM, Tomavo S, Nigou J, Brodin P, Cohen-Gonsaud M
Structure 24 1788-1794 (2016)
PMID: 27568926

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-520541 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Protein LppM Chain: A
Molecule details ›
Chain: A
Length: 182 amino acids
Theoretical weight: 19.42 KDa
Source organism: Mycobacterium tuberculosis
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: O53505 (Residues: 26-185; Coverage: 79%)
Gene names: Rv2171, lppM
Sequence domains: LppM domain

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Chemical shift assignment: 82%
Refinement method: distance geometry, simulated annealing
Expression system: Escherichia coli BL21(DE3)

Quick links

Citations

2 mentions without citation

Solution NMR Studies of Mycobacterium tuberculosis Proteins for Antibiotic Target Discovery.
Kim et al. (2017)
1 more