› 2nd5

Solution NMR

Lysine dimethylated FKBP12

Released:
DOI: 10.2210/pdb2nd5/pdb
PDB entry 2nd5 coloured by chain, ensemble of 20 models, front view.
PDB entry 2nd5 coloured by chain, ensemble of 20 models, side view.
PDB entry 2nd5 coloured by chain, ensemble of 20 models, top view.
Source organism: Homo sapiens
Entry authors: Hattori Y, Sebera J, Sychrovsky V, Furuita K, Sugiki T, Ohki I, Ikegami T, Kobayashi N, Tanaka Y, Fujiwara T, Kojima C

Function and Biology Details

Reaction catalysed: 
Peptidylproline (omega=180) = peptidylproline (omega=0)
Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-158812 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Peptidyl-prolyl cis-trans isomerase FKBP1A Chain: A
Molecule details ›
Chain: A
Length: 111 amino acids
Theoretical weight: 12.43 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P62942 (Residues: 1-108; Coverage: 100%)
Gene names: FKBP1, FKBP12, FKBP1A
Sequence domains: FKBP-type peptidyl-prolyl cis-trans isomerase
Structure domains: Chitinase A; domain 3

Ligands and Environments

No bound ligands
1 modified residue:
Ligand MLY 8 x MLY

Experiments and Validation Details

Entry percentile scores
Chemical shift assignment: 92%
Refinement method: simulated annealing
Expression system: Escherichia coli

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