Function and Biology

Human fibroblast growth factor-1 (140 amino acid form) with Cys117Val/Pro134Cys mutations

Source organism: Homo sapiens

GO terms

Biochemical function:
Biological process:
Cellular component:

Sequence family

Pfam Protein family (Pfam)
PF00167
Domain description: Fibroblast growth factor
Occurring in:
  1. Fibroblast growth factor 1
The deposited structure of PDB entry 2ntd contains 4 copies of Pfam domain PF00167 (Fibroblast growth factor) in Fibroblast growth factor 1. Showing 1 copy in chain B.

InterPro InterPro annotations
IPR002209
Domain description: Fibroblast growth factor family
Occurring in:
  1. Fibroblast growth factor 1
IPR008996
Domain description: Cytokine IL1/FGF
Occurring in:
  1. Fibroblast growth factor 1

Structure domain

CATH CATH domain
2.80.10.50
Class: Mainly Beta
Architecture: Trefoil
Topology: Trefoil (Acidic Fibroblast Growth Factor, subunit A)
Homology: Trefoil (Acidic Fibroblast Growth Factor, subunit A)
Occurring in:
  1. Fibroblast growth factor 1
The deposited structure of PDB entry 2ntd contains 4 copies of CATH domain 2.80.10.50 (Trefoil (Acidic Fibroblast Growth Factor, subunit A)) in Fibroblast growth factor 1. Showing 1 copy in chain B.