Function and Biology Details
Reaction catalysed:
ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate
Biochemical function:
Biological process:
Cellular component:
Structure analysis Details
Assembly composition:
hetero tetramer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-138700 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (4 distinct):
Soluble KIT ligand
Molecule details ›
Chains: A, B, E, F
Length: 145 amino acids
Theoretical weight: 16.44 KDa
Source organism: Mus musculus
Expression system: Trichoplusia ni
UniProt:
Sequence domains: Stem cell factor
Structure domains: Growth Hormone; Chain: A;
Length: 145 amino acids
Theoretical weight: 16.44 KDa
Source organism: Mus musculus
Expression system: Trichoplusia ni
UniProt:
- Canonical:
P20826 (Residues: 28-166; Coverage: 56%)
Sequence domains: Stem cell factor
Structure domains: Growth Hormone; Chain: A;
Mast/stem cell growth factor receptor Kit
Molecule details ›
Chains: U, W, X, Y
Length: 290 amino acids
Theoretical weight: 32.27 KDa
Source organism: Mus musculus
Expression system: Escherichia coli BL21
UniProt:
Sequence domains: Immunoglobulin domain
Structure domains: Immunoglobulins
Length: 290 amino acids
Theoretical weight: 32.27 KDa
Source organism: Mus musculus
Expression system: Escherichia coli BL21
UniProt:
- Canonical: P05532 (Residues: 25-314; Coverage: 30%)
Sequence domains: Immunoglobulin domain
Structure domains: Immunoglobulins
Ligands and Environments
Experiments and Validation Details
wwPDB Validation report is not available for this entry.
X-ray source:
APS BEAMLINE 5ID-B
Spacegroup:
P21
Expression systems:
- Trichoplusia ni
- Escherichia coli BL21
