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Solution structure of human interleukin-21

Source organism: Homo sapiens
Biochemical function: protein binding
Biological process: cellular response to virus
Cellular component: extracellular space

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GO terms

Biochemical function:
Biological process:
Cellular component:

Sequence family

Pfam Protein family (Pfam)
PF02372
Domain description: Interleukin 15
Occurring in:
  1. Interleukin-21
The deposited structure of PDB entry 2oqp contains 1 copy of Pfam domain PF02372 (Interleukin 15) in Interleukin-21. Showing 1 copy in chain A.

InterPro InterPro annotations
IPR009079
Domain description: Four-helical cytokine-like, core
Occurring in:
  1. Interleukin-21
IPR003443
Domain description: Interleukin-15/Interleukin-21 family
Occurring in:
  1. Interleukin-21

Structure domain

CATH CATH domain
1.20.1250.70
Class: Mainly Alpha
Architecture: Up-down Bundle
Topology: Growth Hormone; Chain: A;
Homology: Interleukin-15/Interleukin-21
Occurring in:
  1. Interleukin-21
The deposited structure of PDB entry 2oqp contains 1 copy of CATH domain 1.20.1250.70 (Growth Hormone; Chain: A;) in Interleukin-21. Showing 1 copy in chain A.
SCOP SCOP annotation
47286
Class: All alpha proteins
Fold: 4-helical cytokines
Superfamily: 4-helical cytokines
Occurring in:
  1. Interleukin-21
The deposited structure of PDB entry 2oqp contains 1 copy of SCOP domain 47286 (Short-chain cytokines) in Interleukin-21. Showing 1 copy in chain A.

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