› 2ozq

X-ray diffraction
1.8Å resolution

Crystal Structure of apo-MUP

Released:
DOI: 10.2210/pdb2ozq/pdb
PDB entry 2ozq coloured by chain, front view.
PDB entry 2ozq coloured by chain, side view.
PDB entry 2ozq coloured by chain, top view.
Source organism: Mus musculus
Primary publication:
Origin of heat capacity changes in a "nonclassical" hydrophobic interaction.
Syme NR, Dennis C, Phillips SE, Homans SW
OpenAccess logo Chembiochem 8 1509-11 (2007)
PMID: 17625803

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assemblies composition:
monomeric (preferred)
homo dimer
Assembly name:
PDBe Complex ID:
PDB-CPX-145881 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Major urinary protein 2 Chain: A
Molecule details ›
Chain: A
Length: 174 amino acids
Theoretical weight: 20.14 KDa
Source organism: Mus musculus
Expression system: Escherichia coli
UniProt:
  • Canonical: P11589 (Residues: 19-180; Coverage: 100%)
Gene name: Mup2
Sequence domains: Lipocalin / cytosolic fatty-acid binding protein family
Structure domains: Lipocalin

Ligands and Environments

2 bound ligands:
Ligand CD 2 x CD
Ligand NA 5 x NA
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU
Spacegroup: P43212
Unit cell:
a: 53.786Å b: 53.786Å c: 137.521Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.183 0.181 0.233
Expression system: Escherichia coli

Quick links

Citations

9 review citations

A medicinal chemist's guide to molecular interactions.
Bissantz et al. (2010)
8 more

2 mentions without citation

Origin of heat capacity changes in a "nonclassical" hydrophobic interaction.
Syme et al. (2007)
1 more