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Crystal structure of the Escherichia coli regulator of sigma 70, Rsd, in complex with sigma 70 domain 4

Source organism: Escherichia coli
Biochemical function: DNA-binding transcription factor activity
Biological process: regulation of DNA-templated transcription
Cellular component: sigma factor antagonist complex

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GO terms

Sequence families

Pfam Protein families (Pfam)
PF04545
Domain description: Sigma-70, region 4
Occurring in:
  1. RNA polymerase sigma factor RpoD
The deposited structure of PDB entry 2p7v contains 1 copy of Pfam domain PF04545 (Sigma-70, region 4) in RNA polymerase sigma factor RpoD. Showing 1 copy in chain B.

PF04353
Domain description: Regulator of RNA polymerase sigma(70) subunit, Rsd/AlgQ
Occurring in:
  1. Regulator of sigma D
The deposited structure of PDB entry 2p7v contains 1 copy of Pfam domain PF04353 (Regulator of RNA polymerase sigma(70) subunit, Rsd/AlgQ) in Regulator of sigma D. Showing 1 copy in chain A.

InterPro InterPro annotations
IPR000943
Domain description: RNA polymerase sigma-70
Occurring in:
  1. RNA polymerase sigma factor RpoD
IPR007448
Domain description: Regulator of RNA polymerase sigma(70) subunit, Rsd/AlgQ
Occurring in:
  1. Regulator of sigma D
IPR013324
Domain description: RNA polymerase sigma factor, region 3/4-like
Occurring in:
  1. RNA polymerase sigma factor RpoD
IPR007630
Domain description: RNA polymerase sigma-70 region 4
Occurring in:
  1. RNA polymerase sigma factor RpoD
IPR036388
Domain description: Winged helix-like DNA-binding domain superfamily
Occurring in:
  1. RNA polymerase sigma factor RpoD
IPR038309
Domain description: Regulator of RNA polymerase sigma(70) subunit, Rsd/AlgQ superfamily
Occurring in:
  1. Regulator of sigma D
IPR023785
Domain description: Regulator of RNA polymerase sigma(70) subunit, Rsd
Occurring in:
  1. Regulator of sigma D

Structure domains

CATH CATH domains
1.10.10.10
Class: Mainly Alpha
Architecture: Orthogonal Bundle
Topology: Arc Repressor Mutant, subunit A
Homology: Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain
Occurring in:
  1. RNA polymerase sigma factor RpoD
The deposited structure of PDB entry 2p7v contains 1 copy of CATH domain 1.10.10.10 (Arc Repressor Mutant, subunit A) in RNA polymerase sigma factor RpoD. Showing 1 copy in chain B.
1.20.120.1370
Class: Mainly Alpha
Architecture: Up-down Bundle
Topology: Four Helix Bundle (Hemerythrin (Met), subunit A)
Homology: Regulator of RNA polymerase sigma(70) subunit, domain 4
Occurring in:
  1. Regulator of sigma D
The deposited structure of PDB entry 2p7v contains 1 copy of CATH domain 1.20.120.1370 (Four Helix Bundle (Hemerythrin (Met), subunit A)) in Regulator of sigma D. Showing 1 copy in chain A.
SCOP SCOP annotation
88665
Class: All alpha proteins
Fold: DNA/RNA-binding 3-helical bundle
Superfamily: Sigma3 and sigma4 domains of RNA polymerase sigma factors
Occurring in:
  1. RNA polymerase sigma factor RpoD
The deposited structure of PDB entry 2p7v contains 1 copy of SCOP domain 88665 (Sigma4 domain) in RNA polymerase sigma factor RpoD. Showing 1 copy in chain B.

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