› 2pfd

X-ray diffraction
3.42Å resolution

Anisotropically refined structure of FTCD

Released:
DOI: 10.2210/pdb2pfd/pdb
PDB entry 2pfd coloured by chain, front view.
PDB entry 2pfd coloured by chain, side view.
PDB entry 2pfd coloured by chain, top view.
Source organism: Rattus norvegicus
Entry authors: Poon BK, Chen X, Lu M, Quiocho FA, Wang Q, Ma J

Function and Biology Details

Reactions catalysed: 
5-formimidoyltetrahydrofolate + L-glutamate = tetrahydrofolate + N-formimidoyl-L-glutamate
5-formimidoyltetrahydrofolate = 5,10-methenyltetrahydrofolate + NH(3)
Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
homo octamer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-131567 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Formimidoyltransferase-cyclodeaminase Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 541 amino acids
Theoretical weight: 59.4 KDa
Source organism: Rattus norvegicus
Expression system: Escherichia coli BL21
UniProt:
  • Canonical: O88618 (Residues: 1-541; Coverage: 100%)
Gene name: Ftcd
Sequence domains:
Structure domains:

Ligands and Environments

No bound ligands
1 modified residue:
Ligand MSE 36 x MSE

Experiments and Validation Details

Entry percentile scores
Spacegroup: P4
Unit cell:
a: 134.848Å b: 134.848Å c: 156.365Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.3 0.24 0.249
Expression system: Escherichia coli BL21

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