› 2pni

Solution NMR

SOLUTION STRUCTURE AND LIGAND-BINDING SITE OF THE SH3 DOMAIN OF THE P85ALPHA SUBUNIT OF PHOSPHATIDYLINOSITOL 3-KINASE

Released:
DOI: 10.2210/pdb2pni/pdb
PDB entry 2pni coloured by chain, ensemble of 26 models, front view.
PDB entry 2pni coloured by chain, ensemble of 26 models, side view.
PDB entry 2pni coloured by chain, ensemble of 26 models, top view.
Source organism: Bos taurus
Primary publication:
Solution structure and ligand-binding site of the SH3 domain of the p85 alpha subunit of phosphatidylinositol 3-kinase.
Booker GW, Gout I, Downing AK, Driscoll PC, Boyd J, Waterfield MD, Campbell ID
Cell 73 813-22 (1993)
PMID: 7684655

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-150051 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Phosphatidylinositol 3-kinase regulatory subunit alpha Chain: A
Molecule details ›
Chain: A
Length: 86 amino acids
Theoretical weight: 9.65 KDa
Source organism: Bos taurus
Expression system: Not provided
UniProt:
  • Canonical: P23727 (Residues: 1-84; Coverage: 12%)
Gene name: PIK3R1
Structure domains: SH3 Domains

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Expression system: Not provided

Quick links

Citations

23 review citations

Phosphoinositide kinases.
Fruman et al. (1998)
22 more

5 mentions without citation

What lessons can be learned from studying the folding of homologous proteins?
Nickson et al. (2010)
4 more