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Ensemble refinement of the protein crystal structure of At1g76680 from Arabidopsis thaliana

Source organism: Arabidopsis thaliana
Biochemical function: 12-oxophytodienoate reductase activity
Biological process: oxylipin biosynthetic process
Cellular component: cytoplasm

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EC 1.3.1.42: 12-oxophytodienoate reductase

Reaction catalysed:
8-((1R,2R)-3-oxo-2-((Z)-pent-2-enyl)cyclopentyl)octanoate + NADP(+) = (15Z)-12-oxophyto-10,15-dienoate + NADPH
Systematic name:
8-((1R,2R)-3-oxo-2-((Z)-pent-2-enyl)cyclopentyl)octanoate:NADP(+) 4-oxidoreductase
Alternative Name(s):
  • 12-oxo-phytodienoic acid reductase

GO terms

Sequence family

Pfam Protein family (Pfam)
PF00724
Domain description: NADH:flavin oxidoreductase / NADH oxidase family
Occurring in:
  1. 12-oxophytodienoate reductase 1
The deposited structure of PDB entry 2q3r contains 1 copy of Pfam domain PF00724 (NADH:flavin oxidoreductase / NADH oxidase family) in 12-oxophytodienoate reductase 1. Showing 1 copy in chain A.

InterPro InterPro annotations
IPR001155
Domain description: NADH:flavin oxidoreductase/NADH oxidase, N-terminal
Occurring in:
  1. 12-oxophytodienoate reductase 1
IPR045247
Domain description: Oxidoreductase Oye-like
Occurring in:
  1. 12-oxophytodienoate reductase 1
IPR013785
Domain description: Aldolase-type TIM barrel
Occurring in:
  1. 12-oxophytodienoate reductase 1

Structure domain

CATH CATH domain
3.20.20.70
Class: Alpha Beta
Architecture: Alpha-Beta Barrel
Topology: TIM Barrel
Homology: Aldolase class I
Occurring in:
  1. 12-oxophytodienoate reductase 1
The deposited structure of PDB entry 2q3r contains 1 copy of CATH domain 3.20.20.70 (TIM Barrel) in 12-oxophytodienoate reductase 1. Showing 1 copy in chain A.
SCOP SCOP annotation
51396
Class: Alpha and beta proteins (a/b)
Fold: TIM beta/alpha-barrel
Superfamily: FMN-linked oxidoreductases
Occurring in:
  1. 12-oxophytodienoate reductase 1
The deposited structure of PDB entry 2q3r contains 1 copy of SCOP domain 51396 (FMN-linked oxidoreductases) in 12-oxophytodienoate reductase 1. Showing 1 copy in chain A.

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